SrasV1, Main, Exploration, bibRecord, 000363

Prognostic value of NT-proBNP in patients with severe COVID-19

Identifieur interne : 000363 ( Main/Exploration ); précédent : 000362; suivant : 000364

Prognostic value of NT-proBNP in patients with severe COVID-19

Source :

Respiratory Research [ 1465-9921 ] ; 2020.

RBID : PMC:7156898

Abstract

Background

The outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in China has been declared a public health emergency of international concern. The cardiac injury is a common condition among the hospitalized patients with COVID-19. However, whether N terminal pro B type natriuretic peptide (NT-proBNP) predicted outcome of severe COVID-19 patients was unknown.

Methods

The study initially enrolled 102 patients with severe COVID-19 from a continuous sample. After screening out the ineligible cases, 54 patients were analyzed in this study. The primary outcome was in-hospital death defined as the case fatality rate. Research information and following-up data were obtained from their medical records.

Results

The best cut-off value of NT-proBNP for predicting in-hospital death was 88.64 pg/mL with the sensitivity for 100% and the specificity for 66.67%. Patients with high NT-proBNP values (> 88.64 pg/mL) had a significantly increased risk of death during the days of following-up compared with those with low values (≤88.64 pg/mL). After adjustment for potential risk factors, NT-proBNP was independently correlated with in-hospital death.

Conclusion

NT-proBNP might be an independent risk factor for in-hospital death in patients with severe COVID-19.

Trial registration

ClinicalTrials, NCT04292964. Registered 03 March 2020,

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156898

DOI: 10.1186/s12931-020-01352-w
PubMed: 32293449
PubMed Central: 7156898

Affiliations:

République populaire de Chine

Le document en format XML

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<author><name sortKey="You, Lin Na" sort="You, Lin Na" uniqKey="You L" first="Lin-Na" last="You">Lin-Na You</name>
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<author><name sortKey="Zhang, Dong Ying" sort="Zhang, Dong Ying" uniqKey="Zhang D" first="Dong-Ying" last="Zhang">Dong-Ying Zhang</name>
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<series><title level="j">Respiratory Research</title>
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<front><div type="abstract" xml:lang="en"><sec><title>Background</title>
<p id="Par1">The outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in China has been declared a public health emergency of international concern. The cardiac injury is a common condition among the hospitalized patients with COVID-19. However, whether N terminal pro B type natriuretic peptide (NT-proBNP) predicted outcome of severe COVID-19 patients was unknown.</p>
</sec>
<sec><title>Methods</title>
<p id="Par2">The study initially enrolled 102 patients with severe COVID-19 from a continuous sample. After screening out the ineligible cases, 54 patients were analyzed in this study. The primary outcome was in-hospital death defined as the case fatality rate. Research information and following-up data were obtained from their medical records.</p>
</sec>
<sec><title>Results</title>
<p id="Par3">The best cut-off value of NT-proBNP for predicting in-hospital death was 88.64 pg/mL with the sensitivity for 100% and the specificity for 66.67%. Patients with high NT-proBNP values (> 88.64 pg/mL) had a significantly increased risk of death during the days of following-up compared with those with low values (≤88.64 pg/mL). After adjustment for potential risk factors, NT-proBNP was independently correlated with in-hospital death.</p>
</sec>
<sec><title>Conclusion</title>
<p id="Par4">NT-proBNP might be an independent risk factor for in-hospital death in patients with severe COVID-19.</p>
</sec>
<sec><title>Trial registration</title>
<p id="Par5">ClinicalTrials, <ext-link ext-link-type="uri" xlink:href="https://clinicaltrials.gov/ct2/show/NCT04292964">NCT04292964.</ext-link>
 Registered 03 March 2020,</p>
</sec>
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<back><div1 type="bibliography"><listBibl><biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Mahase, E" uniqKey="Mahase E">E Mahase</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Huang, C" uniqKey="Huang C">C Huang</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Jeong, Ky" uniqKey="Jeong K">KY Jeong</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Fernandez, Jf" uniqKey="Fernandez J">JF Fernandez</name>
</author>
<author><name sortKey="Restrepo, Mi" uniqKey="Restrepo M">MI Restrepo</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Akp Nar, Ee" uniqKey="Akp Nar E">EE Akpınar</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Restrepo, Mi" uniqKey="Restrepo M">MI Restrepo</name>
</author>
<author><name sortKey="Reyes, Lf" uniqKey="Reyes L">LF Reyes</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Hill, Sa" uniqKey="Hill S">SA Hill</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Saenger, Ak" uniqKey="Saenger A">AK Saenger</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Shor, R" uniqKey="Shor R">R Shor</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Vallabhajosyula, S" uniqKey="Vallabhajosyula S">S Vallabhajosyula</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Donoghue, M" uniqKey="Donoghue M">M Donoghue</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Chen, C" uniqKey="Chen C">C Chen</name>
</author>
<author><name sortKey="Zhang, Xr" uniqKey="Zhang X">XR Zhang</name>
</author>
<author><name sortKey="Ju, Zy" uniqKey="Ju Z">ZY Ju</name>
</author>
<author><name sortKey="He, Wf" uniqKey="He W">WF He</name>
</author>
</analytic>
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<affiliations><list><country><li>République populaire de Chine</li>
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<name sortKey="Jiang, Dan" sort="Jiang, Dan" uniqKey="Jiang D" first="Dan" last="Jiang">Dan Jiang</name>
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   |wiki=    Sante
   |area=    SrasV1
   |flux=    Main
   |étape=   Exploration
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   |clé=     PMC:7156898
   |texte=   Prognostic value of NT-proBNP in patients with severe COVID-19
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Serveur d'exploration SRAS

Prognostic value of NT-proBNP in patients with severe COVID-19

Prognostic value of NT-proBNP in patients with severe COVID-19

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Abstract

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